Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (0) GO Terms (53) Nucleotides (142) Proteins (56) Interactants (5) Wiki
XB-GENEPAGE-1002434
???displayGene.symbol???:
 gclc

???displayGene.name???: 
glutamate-cysteine ligase, catalytic subunit

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Gamma-glutamylcysteine synthetase

AI Protein Function :
The gclc protein functions as the catalytic subunit of glutamate-cysteine ligase, the rate-limiting enzyme in glutathione biosynthesis. It localizes to the cytoplasm where it catalyzes the formation of...[+]


InterPro :
Gln synth/guanido kin cat dom, GCS

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
congenital nonspherocytic hemolytic anemia 7

MIM:
MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info