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Summary Expression Phenotypes Gene Literature (4) GO Terms (37) Nucleotides (139) Proteins (77) Interactants (214) Wiki
XB-GENEPAGE-1006199
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 otof

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otoferlin

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( Nomenclature history )

???displayGene.geneFunction???
Membrane-associated protein FER-1 and related ferlins, contain multiple C2 domains

AI Protein Function :
The otof gene encodes a multi-C2 domain protein implicated in synaptic vesicle priming and calcium-triggered exocytosis at the ribbon synapses of hair cells in the inner ear and lateral line system. Th...[+]


InterPro :
C2 dom, C2 domain sf, C2C Ferlin, C2D Ferlin, [+]

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Diseases: 


Disease Ontology:
autosomal recessive nonsyndromic deafness [+]

MIM:
DEAFNESS, AUTOSOMAL RECESSIVE 9; DFNB9

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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