Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (11) GO Terms (49) Nucleotides (185) Proteins (54) Interactants (302) Wiki
XB-GENEPAGE-1008433
???displayGene.symbol???:
 map3k1

???displayGene.name???: 
mitogen-activated protein kinase kinase kinase 1

???displayGene.synonyms???
mapkkk1 , mekk , mekk1 ( Nomenclature history )

???displayGene.geneFunction???
MEKK and related serine/threonine protein kinases

AI Protein Function :
The map3k1 gene encodes a serine/threonine protein kinase that functions as an intracellular signaling molecule. This kinase acts within the MAPK/ERK cascade and is involved in regulating cell migratio...[+]


InterPro :
ARM-like, Kinase-like dom sf, MAP kinase kinase kinase, Prot kinase dom, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
46,XY complete gonadal dysgenesis [+]

MIM:
46,XY SEX REVERSAL 6; SRXY6

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info