Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (0) GO Terms (27) Nucleotides (94) Proteins (61) Interactants (25) Wiki
XB-GENEPAGE-1013936
???displayGene.symbol???:
 ccm2

???displayGene.name???: 
CCM2 scaffold protein

???displayGene.synonyms???
c7orf22 , LOC108718459 ( Nomenclature history )

???displayGene.geneFunction???
a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade

AI Protein Function :
The gene ccm2 encodes a scaffold protein which localizes to the cytoplasm, nucleus, and cell junctions. Its function involves cardiovascular development, angiogenesis, and neural tube closure through i...[+]


InterPro :
CCM2 C, PH-like dom sf, Malcavernin, PTB/PI dom

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
cerebral cavernous malformation 2

MIM:
CEREBRAL CAVERNOUS MALFORMATIONS 2; CCM2

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info