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Summary Expression Phenotypes Gene Literature (0) GO Terms (11) Nucleotides (9) Proteins (11) Interactants (0) Wiki
XB-GENEPAGE-29084198
???displayGene.symbol???:
 irs2

???displayGene.name???: 
insulin receptor substrate 2

???displayGene.synonyms???
irsu , LOC100498409 , LOC108708462 , LOC108709741 ( Nomenclature history )

AI Protein Function :
The irs2 protein functions as an insulin receptor substrate, acting as a cytoplasmic signaling scaffold molecule that is tyrosine-phosphorylated in response to ligands like insulin, igf1, and relaxin. ...[+]


InterPro :
IRS, IRS PTB, PH-like dom sf, PH domain

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Diseases: 


Disease Ontology:
type 2 diabetes mellitus

MIM:
TYPE 2 DIABETES MELLITUS; T2D

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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