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Summary Expression Phenotypes Gene Literature (9) GO Terms (27) Nucleotides (11) Proteins (10) Interactants (69) Wiki
XB-GENEPAGE-29099202
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 mpl

???displayGene.name???: 
MPL proto-oncogene, thrombopoietin receptor

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LOC108713530 ( Nomenclature history )

AI Protein Function :
The mpl protein is a transmembrane receptor for thrombopoietin and functions in hematopoiesis by activating the JAK-STAT signaling pathway. It is expressed in blood, liver, and pronephros.


InterPro :
FN3 dom, FN3 sf, Growth/epo recpt lig-bind, Ig-like fold, [+]

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Diseases: 


Disease Ontology:
congenital amegakaryocytic thrombocytopenia [+]

MIM:
MYELOFIBROSIS [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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