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Summary Expression Phenotypes Gene Literature (1) GO Terms (48) Nucleotides (56) Proteins (31) Interactants (199) Wiki
XB-GENEPAGE-483759
???displayGene.symbol???:
 crb1

???displayGene.name???: 
crumbs 1, cell polarity complex component

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( Nomenclature history )

???displayGene.geneFunction???
Fibrillins and related proteins containing Ca2+-binding EGF-like domains

AI Protein Function :
The crb1 protein is a transmembrane protein localized to the apical membrane and adherens junctions of photoreceptors in the retina. It functions in cell adhesion, establishing and maintaining apicobas...[+]


InterPro :
ConA-like dom sf, EGF-like Ca-bd dom, EGF-like CS, EGF-like dom, [+]

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Diseases: 


Disease Ontology:
Leber congenital amaurosis 8 [+]

MIM:
PIGMENTED PARAVENOUS CHORIORETINAL ATROPHY; PPCRA [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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