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Summary Expression Phenotypes Gene Literature (64) GO Terms (64) Nucleotides (488) Proteins (243) Interactants (383) Wiki
XB-GENEPAGE-489247
???displayGene.symbol???:
 nedd4l

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NEDD4 like E3 ubiquitin protein ligase

???displayGene.synonyms???
nedd4-2 ( Nomenclature history )

???displayGene.geneFunction???
ubiquitin-protein ligase

AI Protein Function :
The nedd4l protein is a HECT-type E3 ubiquitin ligase that regulates epithelial sodium channel (ENaC) activity through its ubiquitination, influencing ion transport. It is involved in neural crest cell...[+]


InterPro :
E3 ub ligase SMURF1, HECT dom, Hect E3 ubiquitin ligase, WW dom, [+]

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Diseases: 


Disease Ontology:
periventricular nodular heterotopia

MIM:
PERIVENTRICULAR NODULAR HETEROTOPIA 7; PVNH7

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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