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Summary Expression Phenotypes Gene Literature (40) GO Terms (241) Nucleotides (219) Proteins (53) Interactants (815) Wiki
XB-GENEPAGE-491432
???displayGene.symbol???:
 pten

???displayGene.name???: 
phosphatase and tensin homolog

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( Nomenclature history )

???displayGene.geneFunction???
protein tyrosine phosphatase

AI Protein Function :
Pten is a dual-specificity phosphatase that dephosphorylates phosphatidylinositol (3,4,5)-trisphosphate, thereby negatively regulating the pi3k-akt signaling pathway to control cell proliferation, surv...[+]


InterPro :
Tyr Pase cat, Tensin phosphatase, Bifunc PIno P3 Pase/Pase PTEN, Tyr Pase AS, [+]

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Diseases: 


Disease Ontology:
Cowden syndrome 1 [+]

MIM:
THYROID CANCER, NONMEDULLARY, 2; NMTC2 [+]

External Links:
1/3
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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