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Summary Expression Phenotypes Gene Literature (1) GO Terms (11) Nucleotides (46) Proteins (27) Interactants (157) Wiki
XB-GENEPAGE-5721344
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 wwox

???displayGene.name???: 
WW domain containing oxidoreductase

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( Nomenclature history )

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ubiquitin protein ligase

AI Protein Function :
The wwox gene in Xenopus laevis and Xenopus tropicalis encodes a protein that functions as a tumor suppressor, involved in apoptosis and cell proliferation. It localizes to the cytoplasm and nucleus, a...[+]


InterPro :
NAD(P)-bd dom sf, SDR fam, WW dom, WW dom sf

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Diseases: 


Disease Ontology:
autosomal recessive spinocerebellar ataxia 12 [+]

MIM:
ESOPHAGEAL CANCER [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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