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Summary Expression Phenotypes Gene Literature (0) GO Terms (22) Nucleotides (88) Proteins (32) Interactants (44) Wiki
XB-GENEPAGE-6033728
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 plekhm1

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pleckstrin homology and RUN domain containing M1

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( Nomenclature history )

???displayGene.geneFunction???
Uncharacterized conserved protein, contains C1, PH and RUN domains

AI Protein Function :
The plekhm1 gene encodes a multi-domain scaffolding protein involved in regulating membrane trafficking processes, particularly autophagy and lysosomal function. It localizes to endosomes and lysosomes...[+]


InterPro :
DEF8, Multihaem cyt sf, PH-like dom sf, PH domain, [+]

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Diseases: 


Disease Ontology:
autosomal recessive osteopetrosis 6

MIM:
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 6; OPTB6 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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