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Summary Expression Phenotypes Gene Literature (1) GO Terms (18) Nucleotides (216) Proteins (112) Interactants (49) Wiki
XB-GENEPAGE-6408099
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 mllt10

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MLLT10, histone lysine methyltransferase DOT1L cofactor

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AF10 , LOC108719864 ( Nomenclature history )

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This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene.

AI Protein Function :
The mllt10 gene encodes a transcription cofactor localized to the nucleus. This protein interacts with other transcriptional regulators and chromatin modifiers. It is expressed in developing tissues in...[+]


InterPro :
EPHD, Znf PHD, Znf RING/FYVE/PHD, Zinc finger PHD-type CS, [+]

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Diseases: 


Disease Ontology:
acute myeloid leukemia

MIM:
LEUKEMIA, ACUTE MYELOID; AML

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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