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Summary Expression Phenotypes Gene Literature (2) GO Terms (50) Nucleotides (110) Proteins (52) Interactants (87) Wiki
XB-GENEPAGE-922618
???displayGene.symbol???:
 als2

???displayGene.name???: 
ALS2, alsin Rho guanine nucleotide exchange factor

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alsin , LOC108701459 , LOC121399160 ( Nomenclature history )

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Junctional membrane complex protein Junctophilin and related MORN repeat proteins

AI Protein Function :
The als2 gene encodes a guanine nucleotide exchange factor protein localized to the cytosol. It functions in neuronal maintenance by regulating endosomal trafficking and is associated with the brain, s...[+]


InterPro :
VPS9, DH-domain, DBL dom sf, RCC1/BLIP-II, [+]

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Diseases: 


Disease Ontology:
amyotrophic lateral sclerosis type 2

MIM:
AMYOTROPHIC LATERAL SCLEROSIS 2, JUVENILE; ALS2 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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