Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (1) GO Terms (41) Nucleotides (128) Proteins (33) Interactants (100) Wiki
XB-GENEPAGE-944391
???displayGene.symbol???:
 afg3l2

???displayGene.name???: 
AFG3-like AAA ATPase 2

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
AAA+-type ATPase containing the peptidase M41 domain

AI Protein Function :
The afg3l2 gene encodes an atp-dependent metalloprotease located in the mitochondrial inner membrane. This protein functions in the proteolytic degradation of misfolded proteins and the processing of s...[+]


InterPro :
ATPase AAA core, AAA lid 3, Peptidase M41, P-loop NTPase, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
spastic ataxia 5 [+]

MIM:
SPASTIC ATAXIA 5, AUTOSOMAL RECESSIVE; SPAX5 [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info