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Summary Expression Phenotypes Gene Literature (1) GO Terms (51) Nucleotides (135) Proteins (38) Interactants (82) Wiki
XB-GENEPAGE-961364
???displayGene.symbol???:
 gch1

???displayGene.name???: 
GTP cyclohydrolase 1

???displayGene.synonyms???
LOC108698762 , LOC108699789 ( Nomenclature history )

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GTP cyclohydrolase I

AI Protein Function :
The gch1 gene encodes the enzyme GTP cyclohydrolase I, which catalyzes the first and rate-limiting step in the synthesis of tetrahydrobiopterin (BH4). BH4 is a required cofactor for the hydroxylation o...[+]


InterPro :
GTP CycHdrlase I, GTP CycHdrlase I dom, GTP CycHdrlase I CS, GTP-CH-I C/QueF, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
dopa-responsive dystonia [+]

MIM:
DYSTONIA, DOPA-RESPONSIVE; DRD [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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