Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (12) GO Terms (58) Nucleotides (102) Proteins (39) Interactants (453) Wiki
XB-GENEPAGE-964442
???displayGene.symbol???:
 lig4

???displayGene.name???: 
ligase IV, DNA, ATP-dependent

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
ATP-dependent DNA ligase IV

AI Protein Function :
The lig4 gene encodes a dna ligase involved in non-homologous end joining (nhej) for the repair of double-strand dna breaks. The protein is localized to the nucleus. Expression is detected in the brain...[+]


InterPro :
DNA ligase N sf, BRCT dom sf, LIG4, BRCT dom, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
Omenn syndrome [+]

MIM:
LIG4 SYNDROME [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info