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Summary Expression Phenotypes Gene Literature (1) GO Terms (30) Nucleotides (341) Proteins (41) Interactants (41) Wiki
XB-GENEPAGE-983262
???displayGene.symbol???:
 gpnmb

???displayGene.name???: 
glycoprotein nmb

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( Nomenclature history )

???displayGene.geneFunction???
calcium ion-modulated nonselective cation channel polycystin

AI Protein Function :
The gpnmb protein is a type i transmembrane glycoprotein localized to melanosomes and expressed in melanocytes and retinal pigment epithelium; it functions in melanin synthesis by modulating tyrosinase...[+]


InterPro :
PKD/Chitinase dom, PKD dom, Ig-like fold, PKD dom sf, [+]

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Diseases: 


Disease Ontology:
primary localized cutaneous amyloidosis 3

MIM:
AMYLOIDOSIS, PRIMARY LOCALIZED CUTANEOUS, 3; PLCA3

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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