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Summary Expression Phenotypes Gene Literature (0) GO Terms (22) Nucleotides (107) Proteins (55) Interactants (89) Wiki
XB-GENEPAGE-987087
???displayGene.symbol???:
 dock8

???displayGene.name???: 
dedicator of cytokinesis 8

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( Nomenclature history )

???displayGene.geneFunction???
PH domain-containing protein

AI Protein Function :
The dock8 gene encodes a dedicator of cytokinesis protein functioning as a guanine nucleotide exchange factor for rac and cdc42 small gtpases. It is cytoplasmic and membrane-associated. Its expression ...[+]


InterPro :
DHR-1 domain, C2 Dock-C, DOCK C/D N, DOCK, [+]

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Diseases: 


Disease Ontology:
autosomal dominant intellectual developmental disorder [+]

MIM:
HYPER-IgE SYNDROME 2, AUTOSOMAL RECESSIVE, WITH RECURRENT INFECTIONS; HIES2 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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