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Summary Expression Phenotypes Gene Literature (9) GO Terms (41) Nucleotides (98) Proteins (48) Interactants (103) Wiki
XB-GENEPAGE-988967
???displayGene.symbol???:
 apaf1

???displayGene.name???: 
apoptotic peptidase activating factor 1

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apaf-1 ( Nomenclature history )

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apoptosis/apoptosome scaffold protein with WD-40 domains, caspase recruitment domain (CARD), and an ATPase domain

AI Protein Function :
The apaf1 protein is an apoptotic protease activating factor. it functions as a key component of the apoptosome, which is a multiprotein oligomer that activates caspases to initiate the intrinsic apopt...[+]


InterPro :
WH-like DNA-bd sf, Apaf-1, WD40 repeat CS, DEATH-like dom sf, [+]

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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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