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Summary Expression Phenotypes Gene Literature (0) GO Terms (69) Nucleotides (77) Proteins (44) Interactants (122) Wiki
XB-GENEPAGE-995775
???displayGene.symbol???:
 sorl1

???displayGene.name???: 
sortilin-related receptor, L(DLR class) A repeats containing

???displayGene.synonyms???
gp250 , lr11 , lrp9 , sorla , sorla-1 [-] ( Nomenclature history )

???displayGene.geneFunction???
Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains

AI Protein Function :
The sorl1 gene encodes a transmembrane receptor involved in regulating neural crest cell migration and melanocyte development through modulation of Wnt signaling pathways. It localizes to membrane-boun...[+]


InterPro :
6-blade b-propeller TolB-like, FN3 dom, FN3 sf, Ig-like fold, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Alzheimer's disease [+]

MIM:
ALZHEIMER DISEASE, FAMILIAL, 1; AD1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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