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Summary Expression Phenotypes Gene Literature (6) GO Terms (37) Nucleotides (99) Proteins (29) Interactants (28) Wiki
XB-GENEPAGE-997693
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 smpd1

???displayGene.name???: 
sphingomyelin phosphodiesterase 1

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acid sphingomyelinase , asm , asmase , npd , sphingomyelin phosphodiesterase [-] ( Nomenclature history )

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Acid sphingomyelinase and PHM5 phosphate metabolism protein

AI Protein Function :
The smpd1 gene encodes an acidic sphingomyelinase, which is a lysosomal hydrolase that catalyzes the hydrolysis of sphingomyelin to ceramide and phosphorylcholine. This enzymatic activity is involved i...[+]


InterPro :
Metallo-depent PP-like, Sphingomy PDE, ASMase/PPN1 MPP, Calcineurin-like PHP ApaH, [+]

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Diseases: 


Disease Ontology:
Niemann-Pick disease type A [+]

MIM:
NIEMANN-PICK DISEASE, TYPE A [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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