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XB-ART-11318
Mech Dev 2000 Apr 01;922:291-4. doi: 10.1016/s0925-4773(99)00345-7.
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Expression of CRYP-alpha, LAR, PTP-delta, and PTP-rho in the developing Xenopus visual system.

Johnson KG, Holt CE.


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Receptor protein tyrosine phosphatases (RPTPs), are involved in axon outgrowth and guidance not only in the Drosophila visual system (Garrity et al., 1999. Neuron 22, 707-717) but also in the developing vertebrate retina (Ledig et al., 1999a. J. Cell Biol. 147, 375-388). We have cloned a variety of Xenopus RPTPs, including four RPTPs expressed in the developing visual system (LAR, PTP-delta, CRYP-alpha and PTP-rho). These four RPTPs are transcribed in the developing optic vesicle during differentiation and in overlapping but distinct patterns in the developing retina during retinal layer formation. LAR, PTP-delta, and CRYP-alpha are also expressed in retinal ganglion cells during axonogenesis and during axon guidance from the retina to the optic tectum.

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Species referenced: Xenopus
Genes referenced: ptprd ptprf ptprs ptprt ptpru rho tbx2 tgm2


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