Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
Elementary Ca2+ puffs form the basic building blocks of global Ins(1, 4,5)P3-evoked Ca2+ signals. In Xenopus oocytes, Ca2+ puffs evoked by the high-affinity agonist adenophostin were shorter and smaller than puffs evoked by Ins(1,4,5)P3 and the lower affinity analogue Ins(2,4, 5)P3. Agonist-specific mechanisms, therefore, play a role in shaping local Ca2+ release events, but termination of Ca2+ flux is not delimited simply by agonist dissociation.
Berridge,
Inositol trisphosphate and calcium signalling.
1993, Pubmed
Berridge,
Inositol trisphosphate and calcium signalling.
1993,
Pubmed Berridge,
Spatial and temporal signalling by calcium.
1994,
Pubmed Berridge,
Elementary and global aspects of calcium signalling.
1997,
Pubmed Bezprozvanny,
Inositol (1,4,5)-trisphosphate (InsP3)-gated Ca channels from cerebellum: conduction properties for divalent cations and regulation by intraluminal calcium.
1994,
Pubmed Bootman,
Subcellular Ca2+ signals underlying waves and graded responses in HeLa cells.
1996,
Pubmed Bootman,
Cooking with calcium: the recipes for composing global signals from elementary events.
1997,
Pubmed Bootman,
Imaging the hierarchical Ca2+ signalling system in HeLa cells.
1997,
Pubmed Cameron,
Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux.
1995,
Pubmed Cameron,
FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain.
1997,
Pubmed DeLisle,
Adenophostin A can stimulate Ca2+ influx without depleting the inositol 1,4,5-trisphosphate-sensitive Ca2+ stores in the Xenopus oocyte.
1997,
Pubmed
,
Xenbase Dufour,
Inositol 1,4,5-trisphosphate and calcium regulate the calcium channel function of the hepatic inositol 1,4,5-trisphosphate receptor.
1997,
Pubmed Finch,
Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release.
1991,
Pubmed Hajnóczky,
The inositol trisphosphate calcium channel is inactivated by inositol trisphosphate.
1994,
Pubmed Hannaert-Merah,
Rapid kinetics of myo-inositol trisphosphate binding and dissociation in cerebellar microsomes.
1994,
Pubmed Hill,
Inositol 1,3,4,5-tetrakisphosphate induces Ca2+ sequestration in rat liver cells.
1988,
Pubmed Hirota,
Adenophostin-medicated quantal Ca2+ release in the purified and reconstituted inositol 1,4,5-trisphosphate receptor type 1.
1995,
Pubmed Irvine,
Specificity of inositol trisphosphate-induced calcium release from permeabilized Swiss-mouse 3T3 cells.
1984,
Pubmed Kume,
The Xenopus IP3 receptor: structure, function, and localization in oocytes and eggs.
1993,
Pubmed
,
Xenbase Leibowitz,
Single-channel acetylcholine receptor kinetics.
1984,
Pubmed Lester,
NMDA channel behavior depends on agonist affinity.
1992,
Pubmed Loomis-Husselbee,
Synergistic effects of inositol 1,3,4,5-tetrakisphosphate on inositol 2,4,5-triphosphate-stimulated Ca2+ release do not involve direct interaction of inositol 1,3,4,5-tetrakisphosphate with inositol triphosphate-binding sites.
1996,
Pubmed Lukyanenko,
Termination of Ca2+ release during Ca2+ sparks in rat ventricular myocytes.
1998,
Pubmed Mak,
Single-channel kinetics, inactivation, and spatial distribution of inositol trisphosphate (IP3) receptors in Xenopus oocyte nucleus.
1997,
Pubmed
,
Xenbase Marchant,
Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors.
1997,
Pubmed Meyer,
Kinetics of calcium channel opening by inositol 1,4,5-trisphosphate.
1990,
Pubmed Nunn,
Liver inositol, 1,4,5-trisphosphate-binding sites are the Ca2(+)-mobilizing receptors.
1990,
Pubmed Parker,
A high-resolution, confocal laser-scanning microscope and flash photolysis system for physiological studies.
1997,
Pubmed
,
Xenbase Parker,
Elementary events of InsP3-induced Ca2+ liberation in Xenopus oocytes: hot spots, puffs and blips.
1996,
Pubmed
,
Xenbase Parker,
Inhibition by Ca2+ of inositol trisphosphate-mediated Ca2+ liberation: a possible mechanism for oscillatory release of Ca2+.
1990,
Pubmed
,
Xenbase Parys,
The inositol trisphosphate receptor of Xenopus oocytes.
1995,
Pubmed
,
Xenbase Parys,
Isolation, characterization, and localization of the inositol 1,4,5-trisphosphate receptor protein in Xenopus laevis oocytes.
1992,
Pubmed
,
Xenbase Sun,
A continuum of InsP3-mediated elementary Ca2+ signalling events in Xenopus oocytes.
1998,
Pubmed
,
Xenbase Takahashi,
Adenophostins, newly discovered metabolites of Penicillium brevicompactum, act as potent agonists of the inositol 1,4,5-trisphosphate receptor.
1994,
Pubmed Xiao,
The immunophilin FK506-binding protein modulates Ca2+ release channel closure in rat heart.
1997,
Pubmed Yao,
Quantal puffs of intracellular Ca2+ evoked by inositol trisphosphate in Xenopus oocytes.
1995,
Pubmed
,
Xenbase
