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Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia.
Shi W, Wang HS, Pan Z, Wymore RS, Cohen IS, McKinnon D, Dixon JE.
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1. Three new members of the EAG potassium channel gene family were identified in rat and the complete coding sequence of one of these genes (elk1) was determined by cDNA cloning. 2. The elk1 gene, when expressed in Xenopus oocytes, encodes a slowly activating and slowly deactivating potassium channel. 3. The elk1 gene is expressed in sympathetic ganglia and is also expressed in sciatic nerve. 4. Six of the seven known EAG genes were found to be expressed in rat sympathetic ganglia, suggesting an important functional role for these channels in the sympathetic nervous system.
Belluzzi,
A five-conductance model of the action potential in the rat sympathetic neurone.
1991, Pubmed
Belluzzi,
A five-conductance model of the action potential in the rat sympathetic neurone.
1991,
Pubmed Brown,
Voltage-sensitive K-currents in sympathetic neurons and their modulation by neurotransmitters.
1982,
Pubmed Chen,
Heteromultimeric interactions among K+ channel subunits from Shaker and eag families in Xenopus oocytes.
1996,
Pubmed
,
Xenbase Dixon,
Potassium channel mRNA expression in prevertebral and paravertebral sympathetic neurons.
1996,
Pubmed Frohman,
On beyond classic RACE (rapid amplification of cDNA ends).
1994,
Pubmed Ganetzky,
Neurogenetic analysis of potassium currents in Drosophila: synergistic effects on neuromuscular transmission in double mutants.
1983,
Pubmed Ludwig,
Functional expression of a rat homologue of the voltage gated either á go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart.
1994,
Pubmed
,
Xenbase Meyer,
Characterization of an eag-like potassium channel in human neuroblastoma cells.
1998,
Pubmed Pennefather,
Two distinct Ca-dependent K currents in bullfrog sympathetic ganglion cells.
1985,
Pubmed Robertson,
Potassium currents expressed from Drosophila and mouse eag cDNAs in Xenopus oocytes.
1996,
Pubmed
,
Xenbase Sanguinetti,
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel.
1995,
Pubmed
,
Xenbase Sanguinetti,
Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.
1990,
Pubmed Shi,
Identification of two nervous system-specific members of the erg potassium channel gene family.
1997,
Pubmed
,
Xenbase Spector,
Fast inactivation causes rectification of the IKr channel.
1996,
Pubmed
,
Xenbase Terlau,
Extracellular Mg2+ regulates activation of rat eag potassium channel.
1996,
Pubmed
,
Xenbase Terlau,
Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment.
1997,
Pubmed
,
Xenbase Thompson,
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
1994,
Pubmed Titus,
The Drosophila erg K+ channel polypeptide is encoded by the seizure locus.
1997,
Pubmed Wang,
Potassium currents in rat prevertebral and paravertebral sympathetic neurones: control of firing properties.
1995,
Pubmed Wang,
The seizure locus encodes the Drosophila homolog of the HERG potassium channel.
1997,
Pubmed Warmke,
A distinct potassium channel polypeptide encoded by the Drosophila eag locus.
1991,
Pubmed Warmke,
A family of potassium channel genes related to eag in Drosophila and mammals.
1994,
Pubmed Wei,
Eight potassium channel families revealed by the C. elegans genome project.
1996,
Pubmed
