Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
In Xenopus laevis eight tRNA genes are located in a 3.18 kb tandemly repeated unit. There are 150 copies of the unit at a single locus near the long arm telomere of one of the acrocentric chromosomes in the 14-17 group. Two additional classes of tRNA gene-containing repeats have been isolated (defined by clones p3.1 and p3.2) that have structures related to that of the 3.18 kb unit. Using in situ hybridization at the electron microscopic level, the p3.2 repeats are found clustered at a single locus in the subtelomeric region on one of the submetacentric chromosomes, whereas the p3.1 repeats are clustered at a locus indistinguishable from that containing the 3.18 kb repeats. This suggests that these tDNA tandem repeats can diverge in sequence from each other without being at distantly separated loci.
Clarkson,
Clustering of transfer RNA genes of Xenopus laevis.
1973, Pubmed,
Xenbase
Clarkson,
Clustering of transfer RNA genes of Xenopus laevis.
1973,
Pubmed
,
Xenbase Clarkson,
Reiterated transfer RNA genes of Xenopus laevis.
1973,
Pubmed
,
Xenbase Clarkson,
Isolation and some properties of DNA coding for tRNA1met from Xenopus laevis.
1976,
Pubmed
,
Xenbase Doering,
Identification and genomic organization of human tRNALys genes.
1982,
Pubmed
,
Xenbase Fostel,
Chromosomal location of a major tRNA gene cluster of Xenopus laevis.
1984,
Pubmed
,
Xenbase Gouilloud,
A dispersed tyrosine tRNA gene from Xenopus laevis with high transcriptional activity in vitro.
1986,
Pubmed
,
Xenbase Marçais,
Organization of the variant domains of alpha satellite DNA on human chromosome 21.
1993,
Pubmed Müller,
Nucleotide sequence of genes coding for tRNAPhe and tRNATyr from a repeating unit of X. laevis DNA.
1980,
Pubmed
,
Xenbase Müller,
Sequence of a 3.18 kb tandem repeat of Xenopus laevis DNA containing 8 tRNA genes.
1987,
Pubmed
,
Xenbase Peterson,
Characterization of two xenopus somatic 5S DNAs and one minor oocyte-specific 5S DNA.
1980,
Pubmed
,
Xenbase Reed,
Rapid transfer of DNA from agarose gels to nylon membranes.
1985,
Pubmed Rosenthal,
The genomic organization of dispersed tRNA and 5 S RNA genes in Xenopus laevis.
1983,
Pubmed
,
Xenbase Schmid,
Chromosome banding in Amphibia. XVI. High-resolution replication banding patterns in Xenopus laevis.
1991,
Pubmed
,
Xenbase Sims,
DNA methylation patterns in the 5S DNAs of Xenopus laevis.
1983,
Pubmed
,
Xenbase Smith,
Evolution of repeated DNA sequences by unequal crossover.
1976,
Pubmed Stutz,
Oocyte and somatic tyrosine tRNA genes in Xenopus laevis.
1989,
Pubmed
,
Xenbase Warburton,
Genomic analysis of sequence variation in tandemly repeated DNA. Evidence for localized homogeneous sequence domains within arrays of alpha-satellite DNA.
1990,
Pubmed Wevrick,
Physical map of the centromeric region of human chromosome 7: relationship between two distinct alpha satellite arrays.
1991,
Pubmed
