Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Homeobox genes are expressed in the retina and brain of adult goldfish.
Levine EM, Schechter N.
???displayArticle.abstract???
The goldfish (Carassius auratus) visual pathway displays continuous growth and plasticity throughout life. Since homeobox genes are important transcriptional regulators in development, we searched for homeobox genes in the adult goldfish retina and brain. Using the PCR, we discovered a repertoire of homeobox sequences expressed in these tissues. In addition to isolating homeodomain sequences found in the vertebrate Hox gene clusters, a sequence identical to the chicken CHox7 homeodomain was characterized. Furthermore, a sequence with significant homologies to the Xenopus XIHbox8 and leech Htr-A2 homeodomains was identified, and these sequences may define an additional class of homeodomain. Finally, a sequence belonging to the paired class (prd) of homeodomains is reported. Homeobox gene expression in the adult goldfish retina and brain may be associated with the persistent developmental features of these tissues.
Acampora,
The human HOX gene family.
1989,
Pubmed Baron,
Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex.
1987,
Pubmed Boncinelli,
Organization of human class I homeobox genes.
1989,
Pubmed Bopp,
Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila.
1986,
Pubmed Brown,
Identification and expression of a regeneration-specific homeobox gene in the newt limb blastema.
1991,
Pubmed Devereux,
A comprehensive set of sequence analysis programs for the VAX.
1984,
Pubmed Easter,
An evaluation of the hypothesis of shifting terminals in goldfish optic tectum.
1984,
Pubmed Fainsod,
A chicken homeo box gene with developmentally regulated expression.
1989,
Pubmed Frohman,
Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm.
1990,
Pubmed Giordano,
A type II keratin is expressed in glial cells of the goldfish visual pathway.
1989,
Pubmed Glasgow,
Plasticin, a novel type III neurofilament protein from goldfish retina: increased expression during optic nerve regeneration.
1992,
Pubmed Gruss,
Pax in development.
1992,
Pubmed Harvey,
Embryonic expression and nuclear localization of Xenopus homeobox (Xhox) gene products.
1986,
Pubmed
,
Xenbase Hawkins,
Homeobox containing genes in the nematode Caenorhabditis elegans.
1990,
Pubmed Heacock,
Enhanced labeling of a retinal protein during regeneration of optic nerve in goldfish.
1976,
Pubmed Hill,
A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.
1989,
Pubmed Hitchcock,
Local regeneration in the retina of the goldfish.
1992,
Pubmed Holland,
Cloning and evolutionary analysis of msh-like homeobox genes from mouse, zebrafish and ascidian.
1991,
Pubmed James,
Homeobox gene expression in the intestinal epithelium of adult mice.
1991,
Pubmed Johns,
Genesis of rods in teleost fish retina.
,
Pubmed Johns,
Growth of the adult goldfish eye. II. Increase in retinal cell number.
1977,
Pubmed Kessel,
Murine developmental control genes.
1990,
Pubmed Kongsuwan,
Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages.
1988,
Pubmed Krauss,
Expression pattern of zebrafish pax genes suggests a role in early brain regionalization.
1991,
Pubmed Krauss,
Zebrafish pax[zf-a]: a paired box-containing gene expressed in the neural tube.
1991,
Pubmed Laughon,
DNA binding specificity of homeodomains.
1991,
Pubmed McGinnis,
A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans.
1984,
Pubmed Meyer,
Evidence from thymidine labeling for continuing growth of retina and tectum in juvenile goldfish.
1978,
Pubmed Monaghan,
The Msh-like homeobox genes define domains in the developing vertebrate eye.
1991,
Pubmed Murtha,
Detection of homeobox genes in development and evolution.
1991,
Pubmed Njølstad,
Primary structure, developmentally regulated expression and potential duplication of the zebrafish homeobox gene ZF-21.
1988,
Pubmed Perry,
Fast axonally transported proteins in regenerating goldfish optic axons.
1987,
Pubmed Püschel,
Sequence and expression pattern of pax-6 are highly conserved between zebrafish and mice.
1992,
Pubmed Raymond,
Regeneration of goldfish retina: rod precursors are a likely source of regenerated cells.
1988,
Pubmed Raymond,
Germinal cells in the goldfish retina that produce rod photoreceptors.
1987,
Pubmed Robert,
Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.
1989,
Pubmed Savard,
Position dependent expression of a homeobox gene transcript in relation to amphibian limb regeneration.
1988,
Pubmed
,
Xenbase Scott,
The structure and function of the homeodomain.
1989,
Pubmed Scott,
Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila.
1984,
Pubmed Shen,
Modulation of homeobox gene expression alters the phenotype of human hematopoietic cell lines.
1992,
Pubmed SPERRY,
CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS.
1963,
Pubmed Stornaiuolo,
Human HOX genes are differentially activated by retinoic acid in embryonal carcinoma cells according to their position within the four loci.
1990,
Pubmed Thor,
The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat.
1991,
Pubmed Walther,
Pax-6, a murine paired box gene, is expressed in the developing CNS.
1991,
Pubmed Wedden,
Expression pattern of homeobox-containing genes during chick embryogenesis.
1989,
Pubmed Wedeen,
Evidence for a new family of evolutionarily conserved homeobox genes.
1990,
Pubmed
,
Xenbase
