Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
Gene transfer studies have shown that estrogen regulation of specific genes is mediated by estrogen response elements (ERE). We report that binding of the estrogen receptor to the ERE can be detected by a gel retardation (band shift) assay. This binding interaction was highly sequence and receptor specific. Methylation interference analysis showed that the ERE contact sites of estrogen receptor displayed a perfect twofold rotational symmetry. This is compatible with estrogen receptor binding to the ERE as a head-to-head dimer.
Bradshaw,
A far upstream ovalbumin enhancer binds nuclear factor-1-like factor.
1988, Pubmed
Bradshaw,
A far upstream ovalbumin enhancer binds nuclear factor-1-like factor.
1988,
Pubmed Burch,
Two functional estrogen response elements are located upstream of the major chicken vitellogenin gene.
1988,
Pubmed Chandler,
DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo.
1983,
Pubmed de Vries,
Contactpoint analysis of the HeLa nuclear factor I recognition site reveals symmetrical binding at one side of the DNA helix.
1987,
Pubmed Dignam,
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.
1983,
Pubmed Evans,
The steroid and thyroid hormone receptor superfamily.
1988,
Pubmed Feavers,
Interaction of two nonhistone proteins with the estradiol response element of the avian vitellogenin gene modulates the binding of estradiol-receptor complex.
1987,
Pubmed Fried,
Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis.
1981,
Pubmed Godowski,
Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement.
,
Pubmed Gorman,
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.
1982,
Pubmed Green,
A superfamily of potentially oncogenic hormone receptors.
,
Pubmed Greene,
Immunochemical studies of estrogen receptors.
1984,
Pubmed Hollenberg,
Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor.
1987,
Pubmed Hope,
Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast.
1986,
Pubmed Jones,
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro.
1985,
Pubmed Jost,
Preferential binding of estrogen-receptor complex to a region containing the estrogen-dependent hypomethylation site preceding the chicken vitellogenin II gene.
1984,
Pubmed Kawai,
New procedure for DNA transfection with polycation and dimethyl sulfoxide.
1984,
Pubmed Keegan,
Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein.
1986,
Pubmed Klein-Hitpass,
Synergism of closely adjacent estrogen-responsive elements increases their regulatory potential.
1988,
Pubmed
,
Xenbase Klein-Hitpass,
A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor.
1988,
Pubmed
,
Xenbase Klein-Hitpass,
An estrogen-responsive element derived from the 5' flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells.
1986,
Pubmed
,
Xenbase Klock,
Oestrogen and glucocorticoid responsive elements are closely related but distinct.
,
Pubmed Lopata,
High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment.
1984,
Pubmed Luckow,
CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements.
1987,
Pubmed Maniatis,
Regulation of inducible and tissue-specific gene expression.
1987,
Pubmed Martinez,
The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element.
1987,
Pubmed
,
Xenbase Maurer,
Identification of an estrogen-responsive element from the 5'-flanking region of the rat prolactin gene.
1987,
Pubmed Maxam,
A new method for sequencing DNA.
1977,
Pubmed Miller,
Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.
1985,
Pubmed
,
Xenbase Ponta,
Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties.
1985,
Pubmed Sanger,
DNA sequencing with chain-terminating inhibitors.
1977,
Pubmed Scheidereit,
Molecular model of the interaction between the glucocorticoid receptor and the regulatory elements of inducible genes.
1986,
Pubmed Seiler-Tuyns,
Identification of estrogen-responsive DNA sequences by transient expression experiments in a human breast cancer cell line.
1986,
Pubmed
,
Xenbase Strähle,
A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression.
1987,
Pubmed Sullivan,
Preparation of monoclonal antibodies to the avian progesterone receptor.
1986,
Pubmed ten Heggeler-Bordier,
Electron microscopic visualization of protein-DNA interactions at the estrogen responsive element and in the first intron of the Xenopus laevis vitellogenin gene.
1987,
Pubmed
,
Xenbase Tsai,
Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II).
1987,
Pubmed Tsai,
Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation.
1988,
Pubmed Walker,
Sequence homologies in the region preceding the transcription initiation site of the liver estrogen-responsive vitellogenin and apo-VLDLII genes.
1984,
Pubmed
,
Xenbase Waterman,
A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene.
1988,
Pubmed Yamamoto,
Steroid receptor regulated transcription of specific genes and gene networks.
1985,
Pubmed
