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snRNAs with properties closely related to those of the major vertebrate U-snRNAs are present in the fungi Aspergillus nidulans, Neurospora crassa and Schizosaccharomyces pombe. These RNAs possess a tri-methyl guanosine cap structure and a subset cross-hybridizes with human U1 and U2 clones. In the form of snRNPs, snRNAs from these fungi as well as from Saccharomyces cerevisiae and pea plants are immunoprecipitated by human and anti-Sm or anti-(U1)RNP autoimmune antibodies. On micro-injection into the cytoplasm of Xenopus oocytes, the snRNAs are packaged into ribonucleoprotein particles and migrate into the nucleus. The results demonstrate a hitherto unsuspected degree of evolutionary conservation in snRNA structure, snRNP protein structure, and sites of RNA-protein interaction within snRNPs.
Ares,
U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs.
1986, Pubmed
Ares,
U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs.
1986,
Pubmed Ballance,
Transformation of Aspergillus nidulans by the orotidine-5'-phosphate decarboxylase gene of Neurospora crassa.
1983,
Pubmed Beggs,
Abnormal expression of chromosomal rabbit beta-globin gene in Saccharomyces cerevisiae.
1980,
Pubmed Berget,
U1, U2, and U4/U6 small nuclear ribonucleoproteins are required for in vitro splicing but not polyadenylation.
1986,
Pubmed Black,
U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing.
1985,
Pubmed Black,
Pre-mRNA splicing in vitro requires intact U4/U6 small nuclear ribonucleoprotein.
1986,
Pubmed Boel,
Two different types of intervening sequences in the glucoamylase gene from Aspergillus niger.
1984,
Pubmed Branlant,
U2 RNA shares a structural domain with U1, U4, and U5 RNAs.
1982,
Pubmed Bringmann,
5'-terminal caps of snRNAs are accessible for reaction with 2,2,7-trimethylguanosine-specific antibody in intact snRNPs.
1983,
Pubmed Busch,
SnRNAs, SnRNPs, and RNA processing.
1982,
Pubmed Chabot,
The 3' splice site of pre-messenger RNA is recognized by a small nuclear ribonucleoprotein.
1985,
Pubmed Cove,
The induction and repression of nitrate reductase in the fungus Aspergillus nidulans.
1966,
Pubmed De Robertis,
Intracellular transport of microinjected 5S and small nuclear RNAs.
1982,
Pubmed
,
Xenbase Forbes,
Small nuclear RNA transcription and ribonucleoprotein assembly in early Xenopus development.
1983,
Pubmed
,
Xenbase Francoeur,
Synthesis of small nuclear ribonucleoprotein particles by the malarial parasite Plasmodium falciparum.
1985,
Pubmed Galli,
Biochemical complementation with RNA in the Xenopus oocyte: a small RNA is required for the generation of 3' histone mRNA termini.
1983,
Pubmed
,
Xenbase Georgiev,
The conserved CAAGAAAGA spacer sequence is an essential element for the formation of 3' termini of the sea urchin H3 histone mRNA by RNA processing.
1985,
Pubmed Käufer,
Fission yeast Schizosaccharomyces pombe correctly excises a mammalian RNA transcript intervening sequence.
,
Pubmed Keller,
Intron splicing: a conserved internal signal in introns of animal pre-mRNAs.
1984,
Pubmed Kinnaird,
The complete nucleotide sequence of the Neurospora crassa am (NADP-specific glutamate dehydrogenase) gene.
1983,
Pubmed Krainer,
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro.
1985,
Pubmed Krämer,
The 5' terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors.
1984,
Pubmed Krol,
U1, U2 and U5 small nuclear RNAs are found in plants cells. Complete nucleotide sequence of the U5 RNA family from pea nuclei.
1983,
Pubmed Langford,
Evidence for an intron-contained sequence required for the splicing of yeast RNA polymerase II transcripts.
1983,
Pubmed Langford,
Yeast is unable to excise foreign intervening sequences from hybrid gene transcripts.
1983,
Pubmed Lerner,
Are snRNPs involved in splicing?
1980,
Pubmed Lerner,
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus.
1979,
Pubmed Luhrmann,
Isolation and characterization of rabbit anti-m3 2,2,7G antibodies.
1982,
Pubmed Mattaj,
Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins.
1985,
Pubmed
,
Xenbase Mattaj,
Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding.
1986,
Pubmed
,
Xenbase Mattaj,
Monospecific antibodies reveal details of U2 snRNP structure and interaction between U1 and U2 snRNPs.
1986,
Pubmed
,
Xenbase Miller,
Direct and indirect gene replacements in Aspergillus nidulans.
1985,
Pubmed Mount,
The U1 small nuclear RNA-protein complex selectively binds a 5' splice site in vitro.
1983,
Pubmed Mount,
A catalogue of splice junction sequences.
1982,
Pubmed Padgett,
Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein.
1983,
Pubmed Pettersson,
The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.
1984,
Pubmed Pikielny,
Evidence for the biochemical role of an internal sequence in yeast nuclear mRNA introns: implications for U1 RNA and metazoan mRNA splicing.
1983,
Pubmed Pikielny,
Specific small nuclear RNAs are associated with yeast spliceosomes.
1986,
Pubmed Reddy,
Primary and secondary structure of U8 small nuclear RNA.
1985,
Pubmed Strub,
Genetic complementation in the Xenopus oocyte: co-expression of sea urchin histone and U7 RNAs restores 3' processing of H3 pre-mRNA in the oocyte.
1986,
Pubmed
,
Xenbase Strub,
The cDNA sequences of the sea urchin U7 small nuclear RNA suggest specific contacts between histone mRNA precursor and U7 RNA during RNA processing.
1984,
Pubmed
,
Xenbase Tilburn,
Transformation by integration in Aspergillus nidulans.
1983,
Pubmed Tollervey,
A U4-like small nuclear RNA is dispensable in yeast.
1983,
Pubmed Tollervey,
Deletion of a yeast small nuclear RNA gene impairs growth.
1985,
Pubmed Van Arsdell,
Pseudogenes for human U2 small nuclear RNA do not have a fixed site of 3' truncation.
1984,
Pubmed Watts,
Aberrant splicing of Drosophila alcohol dehydrogenase transcripts in Saccharomyces cerevisiae.
1983,
Pubmed Wise,
Yeast contains small nuclear RNAs encoded by single copy genes.
1983,
Pubmed Yelton,
Transformation of Aspergillus nidulans by using a trpC plasmid.
1984,
Pubmed Zeller,
Nucleocytoplasmic distribution of snRNPs and stockpiled snRNA-binding proteins during oogenesis and early development in Xenopus laevis.
1983,
Pubmed
,
Xenbase
