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EMBO J
1983 Jan 01;23:443-8. doi: 10.1002/j.1460-2075.1983.tb01442.x.
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Patterns of major divergence between the internal transcribed spacers of ribosomal DNA in Xenopus borealis and Xenopus laevis, and of minimal divergence within ribosomal coding regions.
Furlong JC, Maden BE.
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We have determined the nucleotide sequences of the two internal transcribed spacers, the adjacent ribosomal coding sequences and the boundary between the external transcribed spacer and the 18S coding sequence in a cloned ribosomal transcription unit from Xenopus borealis. The transcribed spacers differ very extensively from those of X. laevis. Nevertheless, embedded in the internal transcribed spacers are several short sequence elements which are identical between the two species. These conserved elements are laterally displaced by substantial distances in the X. borealis sequence with respect to that of X. laevis. These relative displacements imply that insertions and deletions have played a major role in transcribed spacer divergence in Xenopus. This in turn implies that large regions of the transcribed spacers do not play a sequence-specific role in ribosome maturation. In contrast, the sequenced parts of the ribosomal coding regions, which encompass 670 nucleotides, differ at only three points from the corresponding sequences in X. laevis, each by a single substitution. These substitutions are readily accommodated by current models for rRNA higher order structure.
Bram,
The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli.
1980, Pubmed
Bram,
The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli.
1980,
Pubmed Brown,
Xenopus borealis misidentified as Xenopus mulleri.
1977,
Pubmed
,
Xenbase Brown,
A comparison of the ribosomal DNA's of Xenopus laevis and Xenopus mulleri: the evolution of tandem genes.
1972,
Pubmed
,
Xenbase Ford,
The nucleotide sequences of 5.8-S ribosomal RNA from Xenopus laevis and Xenopus borealis.
1978,
Pubmed
,
Xenbase Forsheit,
An electron microscope heteroduplex study of the ribosomal DNAs of Xenopus laevis and Xenopus mulleri.
1974,
Pubmed
,
Xenbase Hall,
Nucleotide sequence through the 18S-28S intergene region of a vertebrate ribosomal transcription unit.
1980,
Pubmed
,
Xenbase Jordan,
Sequence of the 3'-terminal portion of Drosophila melanogaster 18 S rRNA and of the adjoining spacer: comparison with corresponding prokaryotic and eukaryotic sequences.
1980,
Pubmed Khan,
Nucleotide sequence relationships between vertebrate 5.8 S ribosomal RNAs.
1977,
Pubmed
,
Xenbase Konkel,
The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.
1979,
Pubmed Maden,
Nucleotide sequence of an external transcribed spacer in Xenopus laevis rDNA: sequences flanking the 5' and 3' ends of 18S rRNA are non-complementary.
1982,
Pubmed
,
Xenbase Maden,
18S coding sequences in amplified ribosomal DNA from Xenopus laevis oocytes are highly homogeneous, unmethylated, and lack major open reading frames.
1982,
Pubmed
,
Xenbase Maden,
Effects of valine deprivation on ribosome formation in HeLa cells.
1969,
Pubmed Maxam,
Sequencing end-labeled DNA with base-specific chemical cleavages.
1980,
Pubmed Michot,
Homology of the 5'-terminal sequence of 28 S rRNA of mouse with yeast and Xenopus. Implication for the secondary structure of the 5.8 S--28 S RNA complex.
1982,
Pubmed
,
Xenbase Moss,
More ribosomal spacer sequences from Xenopus laevis.
1980,
Pubmed
,
Xenbase Nazar,
A 5.8 S rRNA-like sequence in prokaryotic 23 S rRNA.
1980,
Pubmed Pace,
Structure of the 5.8S RNA component of the 5.8S-28S ribosomal RNA junction complex.
1977,
Pubmed Rubtsov,
The structure of the yeast ribosomal RNA genes. I. The complete nucleotide sequence of the 18S ribosomal RNA gene from Saccharomyces cerevisiae.
1980,
Pubmed Salim,
Nucleotide sequence of Xenopus laevis 18S ribosomal RNA inferred from gene sequence.
1981,
Pubmed
,
Xenbase Skriabin,
[Nucleotide sequence of the proposed transcription initiation region of the yeast ribosome operon].
1979,
Pubmed Skriabin,
[Full sequence of the nucleotides of the spacer region located between the genes for yeast 18S and 5.8S RNA].
1979,
Pubmed Smith,
A simple method for DNA restriction site mapping.
1976,
Pubmed Stewart,
Multiple heterogeneities in the transcribed spacers of ribosomal DNA from Xenopus laevis.
1983,
Pubmed
,
Xenbase Stiegler,
A general secondary-structure model for procaryotic and eucaryotic RNAs from the small ribosomal subunits.
1981,
Pubmed
,
Xenbase Subrahmanyam,
Nucleotide sequence of the region between the 18S rRNA sequence and the 28S rRNA sequence of rat ribosomal DNA.
1982,
Pubmed
,
Xenbase Veldman,
The nucleotide sequence of the intergenic region between the 5.8S and 26S rRNA genes of the yeast ribosomal RNA operon. Possible implications for the interaction between 5.8S and 26S rRNA and the processing of the primary transcript.
1981,
Pubmed Veldman,
Some characteristics of processing sites in ribosomal precursor RNA of yeast.
1980,
Pubmed Veldman,
The primary and secondary structure of yeast 26S rRNA.
1981,
Pubmed Walker,
Enzymatic and chemical structure mapping of mouse 28S ribosomal ribonucleic acid contacts in 5.8S ribosomal ribonucleic acid.
1982,
Pubmed Warner,
Nascent ribosomes from HeLa cells.
1967,
Pubmed Wellauer,
Secondary structure maps of ribosomal RNA and DNA. I. Processing of Xenopus laevis ribosomal RNA and structure of single-stranded ribosomal DNA.
1974,
Pubmed
,
Xenbase Willems,
The regulation of RNA synthesis and processing in the nucleolus during inhibition of protein synthesis.
1969,
Pubmed Young,
Complementary sequences 1700 nucleotides apart form a ribonuclease III cleavage site in Escherichia coli ribosomal precursor RNA.
1978,
Pubmed Zwieb,
Secondary structure comparisons between small subunit ribosomal RNA molecules from six different species.
1981,
Pubmed
,
Xenbase
