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Chromosoma
1980 Jan 01;771:83-103. doi: 10.1007/bf00292043.
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Chromosome banding in amphibia. IV. Differentiation of GC- and AT-rich chromosome regions in Anura.
Schmid M.
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The chromosomes of 26 species of Anura from variously highly envolved groups were analysed with the fluorescent GC-specific antibiotics mithramycin and chromomycin A3 as well as with the AT-specific quinacrine. The mithramycin- and chromomycin A3-stainings generally resulted in a pattern of the constitutive heterochromatin opposite to the one obtained with quinacrine stain. The weaker a heterochromatic region fluoresces with quinacrine, the stronger is the intensity of the fluorescence achieved with mithramycin and chromomycin A3. Some of the telomeric and interstitial heterochromatic regions, however, exhibit no enhanced fluorescence with any of the fluorochromes. The nucleolar constrictions of the nucleolus organizer regions (NORs) displayed the brightest mithramycin- and chromomycin A3-fluorescence in the karyotypes and interphase nuclei of all species examined. The contrast of the brightly fluorescing GC-rich heterochromatin and of the NORs is considerably enhanced, when the non-fluorescent AT-specific oligopeptide distamycin A is employed as a counterstain. No banding patterns were observed with the fluorochromes in the euchromatic regions of the metaphase chromosomes; this attributed to the strong spiralization of the anuran chromosomes. A cytochemical classification of the various chromatin types in the anuran chromosomes is discussed on the basis of the differential labelings found on the constitutive heterochromatin by means of the fluorochromes.
Arrighi,
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1974, Pubmed
Arrighi,
The sex chromosomes of the Chinese hamster: constitutive heterochromatin deficient in repetitive DNA sequences.
1974,
Pubmed Behr,
Interaction of the RNA polymerase inhibitor chromomycin with DNA.
1969,
Pubmed Brown,
Gene linkage by RNA-DNA hybridization. II. Arrangement of the redundant gene sequences for 28 s and 18 s ribosomal RNA.
1968,
Pubmed
,
Xenbase Brown,
Specific gene amplification in oocytes. Oocyte nuclei contain extrachromosomal replicas of the genes for ribosomal RNA.
1968,
Pubmed Brown,
A comparison of the ribosomal DNA's of Xenopus laevis and Xenopus mulleri: the evolution of tandem genes.
1972,
Pubmed
,
Xenbase Comings,
Mechanisms of chromosome banding. VIII. Hoechst 33258-DNA interaction.
1975,
Pubmed Engel,
Activation of mouse ribosomal RNA genes at the 2-cell stage.
1977,
Pubmed Goodpasture,
Human nucleolus organizers: the satellites or the stalks?
1976,
Pubmed Goodpasture,
Visualization of nucleolar organizer regions im mammalian chromosomes using silver staining.
1975,
Pubmed Hofgärtner,
Pattern of activity of nucleolus organizers during spermatogenesis in mammals as analyzed by silver-staining.
1979,
Pubmed Howell,
Visualization of ribosomal gene activity: silver stains proteins associated with rRNA transcribed from oocyte chromosomes.
1977,
Pubmed Hsu,
Distribution of constitutive heterochromatin in mamallian chromosomes.
1971,
Pubmed Jalal,
Cytological differentiation of constitutive heterochromatin.
1974,
Pubmed Macgregor,
The chromosomal localization of a heavy satellite DNA in the testis of Plethodon c. cinereus.
1971,
Pubmed Macgregor,
Observations on centromeric heterochromatin and satellite DNA in salamanders of the genus Plethodon.
1973,
Pubmed Macgregor,
In situ hybridization of highly repetitive DNA to chromosomes of Triturus cristatus.
1979,
Pubmed Miller,
Expression of human and suppression of mouse nucleolus organizer activity in mouse-human somatic cell hybrids.
1976,
Pubmed Miller,
Suppression of human nucleolus organizer activity in mouse-human somatic hybrid cells.
1976,
Pubmed Mizuno,
Chromosomes, DNA sequences, and evolution in salamanders of the genus Plethodon.
1974,
Pubmed Müller,
Interactions of heteroaromatic compounds with nucleic acids. A - T-specific non-intercalating DNA ligands.
1975,
Pubmed Nardi,
Chromosome location of the ribosomal RNA genes in Triturus vulgaris meridionalis (Amphibia, Urodela).
1978,
Pubmed Pardue,
Localization of repeated DNA sequences in Xenopus chromosomes.
1974,
Pubmed
,
Xenbase Schnedl,
Mithramycin and DIPI: a pair of fluorochromes specific for GC-and AT-rich DNA respectively.
1977,
Pubmed Schwarzacher,
The nature of the Ag-staining of nucleolus organizer regions. Electron- and light-microscopic studies on human cells in interphase, mitosis, and meiosis.
1978,
Pubmed Schweizer,
Modification of DAPI banding on human chromosomes by prestaining with a DNA-binding oligopeptide antibiotic, distamycin A.
1978,
Pubmed Schweizer,
Heterochromatin diversity in Cymbidium, and its relationship to differential DNA replication.
1976,
Pubmed Schweizer,
Reverse fluorescent chromosome banding with chromomycin and DAPI.
1976,
Pubmed Sinclair,
Retention of common nucleotide sequences in the ribosomal deoxyribonucleic acid of eukaryotes and some of their physical characteristics.
1971,
Pubmed Thiébaud,
Quantitative determination of amplified rDNA and its distribution during oogenesis in Xenopus laevis.
1979,
Pubmed
,
Xenbase Thiébaud,
The intra-nucleolar localization of amplified rDNA in Xenopus laevis oocytes.
1979,
Pubmed
,
Xenbase Ullerich,
[Further studies on chromosome proportions and DNA-contents in anurans (Amphibia)].
1967,
Pubmed Vlad,
Quantitative studies of rDNA in amphibians.
1977,
Pubmed Ward,
Base specificity in the interaction of polynucleotides with antibiotic drugs.
1965,
Pubmed Weisblum,
Quinacrine, a chromosome stain specific for deoxyadenylate-deoxythymidylaterich regions in DNA.
1972,
Pubmed Weisblum,
Why centric regions of guinacrine-tested mouse chromosomes show diminished fluorescence.
1973,
Pubmed Weisblum,
Fluorescent probes of chromosomal DNA structure: three classes of acridines.
1974,
Pubmed Zimmer,
Effects of the antibiotics netropsin and distamycin A on the structure and function of nucleic acids.
1975,
Pubmed