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Induction of maturation (meiosis) in small Xenopus laevis oocytes by injection of maturation promoting factor.
Hanocq-Quertier J, Baltus E, Brachet J.
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Treatment of small-(stage III) or medium-sized (stage IV) Xenopus laevis oocytes with progesterone, human chorionic gonadotropin, or para-hydroxymercuriphenylsulfonate does not induce maturation. Only the full-grown oocytes (stage VI) undergo maturation when treated with either one of these three substances. In contrast, injection of maturation promoting factor into oocytes of stages III-VI invariably leads to chromosome condensation and germinal vesicle breakdown. No maturation spindle is found in oocytes smaller than 0.9 nm in diameter, and the nuclear sap does not mix with the cytoplasm in the smallest (0.45-0.55 mm in diameter) oocytes. In oocytes of 0.9 mm, maturation is identical to that of full-grown oocytes, except that the maturation spindle does not reach the cortex of the oocyte. Progesterone increases protein synthesis in medium-sized (0.8 mm in diameter) oocytes without inducing meiosis. It has little or no effect on protein synthesis in smaller oocytes.
Bellé,
Nature of progesterone action on amino acid uptake by isolated full-grown oocyte of Xenopus laevis.
1976, Pubmed,
Xenbase
Bellé,
Nature of progesterone action on amino acid uptake by isolated full-grown oocyte of Xenopus laevis.
1976,
Pubmed
,
Xenbase Bellé,
In vitro progesterone binding to Xenopus laevis oocytes.
1975,
Pubmed
,
Xenbase Benbow,
Cytoplasmic control of nuclear DNA synthesis during early development of Xenopus laevis: a cell-free assay.
1975,
Pubmed
,
Xenbase Brachet,
Biochemical changes during progesterone-induced maturation in Xenopus laevis oocytes.
1974,
Pubmed
,
Xenbase Brachet,
Studies on maturation in Xenopus laevis oocytes. III. Energy production and requirements for protein synthesis.
1975,
Pubmed
,
Xenbase Brachet,
Induction of maturation (meiosis) in Xenopus laevis oocytes by three organomercurials.
1975,
Pubmed
,
Xenbase Bradbury,
Molecular basis of control of mitotic cell division in eukaryotes.
1974,
Pubmed Drury,
Effects of cycloheximide on the "autocatalytic" nature of the maturation promoting factor (MPF) in oocytes of Xenopus laevis.
1975,
Pubmed
,
Xenbase Dumont,
Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals.
1972,
Pubmed
,
Xenbase Grippo,
DNA polymerase activity during maturation in Xenopus laevis oocytes.
1972,
Pubmed
,
Xenbase Hallberg,
In vivo and in vitro hormonal effects on the metabolism of immature oocytes of Xenopus laevis.
1976,
Pubmed
,
Xenbase Jacobelli,
Hormone-induced maturation of Xenopus laevis oocytes: effects of different steroids and study of the properties of a progesterone receptor.
1974,
Pubmed
,
Xenbase Masui,
Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes.
1971,
Pubmed Pestell,
Microtubule protein synthesis during oogenesis and early embryogenesis in Xenopus laevis.
1975,
Pubmed
,
Xenbase Reynhout,
Studies on the appearance and nature of a maturation-inducing factor in the cytoplasm of amphibian oocytes exposed to progesterone.
1974,
Pubmed
,
Xenbase Reynhout,
Response of large oocytes of Xenopus laevis to progesterone in vitro in relation to oocyte size and time after previous HCG-induced ovulation.
1975,
Pubmed
,
Xenbase Schorderet-Slatkine,
Action of progesterone and related steroids on oocyte maturation in Xenopus laevis. An in vitro study.
1972,
Pubmed
,
Xenbase Schorderet-Slatkine,
Progesterone induced maturation in oocytes of Xenopus laevis. Appearance of a 'maturation promoting factor' in enucleated oocytes.
1973,
Pubmed
,
Xenbase Smith,
Role of the oocyte nucleus in physiological maturation in Rana pipiens.
1969,
Pubmed Smith,
Regulatory processes in the maturation and early cleavage of amphibian eggs.
1970,
Pubmed Smith,
The interaction of steroids with Rana pipiens Oocytes in the induction of maturation.
1971,
Pubmed Wallace,
Protein incorporation by isolated amphibian oocytes. 3. Optimum incubation conditions.
1973,
Pubmed
,
Xenbase Wasserman,
Effects of cyclohexamide on a cytoplasmic factor initiating meiotic naturation in Xenopus oocytes.
1975,
Pubmed
,
Xenbase Wasserman,
A cytoplasmic factor promoting oocyte maturation: its extraction and preliminary characterization.
1976,
Pubmed
,
Xenbase Wiblet,
[Meiosis: role of a histone kinase in the condensation of ovarian oocyte chromosomes of Xenopus laevis and Ambystoma mexicanum].
1975,
Pubmed
,
Xenbase Wiblet,
Protein kinase activities during maturation in Xenopus laevis oocytes.
1974,
Pubmed
,
Xenbase
