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Effects of ionic concentration on sodium permeability properties of myelinated nerve fibres of Xenopus laevis.
Brismar T, Frankenhaeuser B.
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1. The nodal currents of single myelinated nerve fibres were recorded under potential clamp conditions, and the effect of [Ca], [Na] and [K] in the external solution on some of the Na permeability properties were analysed. 2. [Ca], [Na] and [K] all affected the position of the steady-state Na inactivation (h) curve on the potential axis. The curve was displaced in positive direction by high ionic concentration. 3. The shift associated to different [Ca] was largest in low [Na] and [K]. Similarly the shift associated to different [Na] and [K] was largest in low [Ca]. 4. The maximum peak sodium permeability (max. peak - PNa) was affected by the [Ca], [Na] and [K]. It was greater in (i) low [Ca], (ii) high ([Na] + [K]) and (iii) high [Na]:[K] ratio. 5. The effect of [Ca] on peak - Na was mainly a consequence of a change in PNa (which is the value of PNa if activation were complete, m = 1, and inactivation fully removed, h = 1).
Armstrong,
Destruction of sodium conductance inactivation in squid axons perfused with pronase.
1973, Pubmed
Armstrong,
Destruction of sodium conductance inactivation in squid axons perfused with pronase.
1973,
Pubmed Brismar,
Effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of Xenopus laevis. Potential clamp experiments.
1973,
Pubmed
,
Xenbase Brismar,
The effect of calcium on the potassium permeability in the myelinated nerve fibre of Xenopus laevis.
1972,
Pubmed
,
Xenbase Chandler,
The effect of changing the internal solution on sodium inactivation and related phenomena in giant axons.
1965,
Pubmed DODGE,
Membrane currents in isolated frog nerve fibre under voltage clamp conditions.
1958,
Pubmed DODGE,
Sodium currents in the myelinated nerve fibre of Xenopus laevis investigated with the voltage clamp technique.
1959,
Pubmed
,
Xenbase FRANKENHAEUSER,
Quantitative description of sodium currents in myelinated nerve fibres of Xenopus laevis.
1960,
Pubmed
,
Xenbase FRANKENHAEUSER,
The effect of calcium on the myelinated nerve fibre.
1957,
Pubmed FRANKENHAEUSER,
The action of calcium on the electrical properties of squid axons.
1957,
Pubmed FRANKENHAEUSER,
THE SPECIFICITY OF THE INITIAL CURRENT IN MYELINATED NERVE FIBRES OF XENOPUS LAEVIS. VOLTAGE CLAMP EXPERIMENTS.
1963,
Pubmed
,
Xenbase FRANKENHAEUSER,
THE ACTION POTENTIAL IN THE MYELINATED NERVE FIBER OF XENOPUS LAEVIS AS COMPUTED ON THE BASIS OF VOLTAGE CLAMP DATA.
1964,
Pubmed
,
Xenbase Goldman,
POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES.
1943,
Pubmed Hille,
Charges and potentials at the nerve surface. Divalent ions and pH.
1968,
Pubmed HODGKIN,
The effect of sodium ions on the electrical activity of giant axon of the squid.
1949,
Pubmed HODGKIN,
A quantitative description of membrane current and its application to conduction and excitation in nerve.
1952,
Pubmed HODGKIN,
The dual effect of membrane potential on sodium conductance in the giant axon of Loligo.
1952,
Pubmed Mozhayeva,
Effect of surface charge on the steady-state potassium conductance of nodal membrane.
1970,
Pubmed Vogel,
Calcium and lanthanum effects at the nodal membrane.
1974,
Pubmed
,
Xenbase
