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Induction of maturation (meiosis) in Xenopus laevis oocytes by three organomercurials.
Brachet J, Baltus E, De Schutter-Pays A, Hanocq-Quertier J, Hubert E, Steinert G.
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Three organomercurials, p-hydroxymercuribenzoate, p-hydroxymercuriphenylsulfonate, and mersalyl, induce maturation (meiosis) in a large percentage (20-100 percent) of Xenopus laevis oocytes. Maturation takes place even when the follicle cells which surround the oocytes have been withdrawn. Organomercurial- and progesterone-induced maturations have many features in common: they do not occur when the inducer is injected into the oocytes, they require the presence of Ca++ in the medium, they are inhibited by cycloheximide but not by actinomycin D. In both cases, the maturation producing factor and the pseudomaturation inducing factor are produced. Organomercurial-treated oocytes react normally to activating stimuli; their protein synthesis increases, but uptake of amino acids is strongly inhibited. Progesterone and p-hydroxymercuriphenyl-sulfonate act synergically in inducing maturation. The main difference between the two agents is that p-hydroxymercuriphenylsulfonate must act for several hours, whereas, short contact with progesterone is sufficient to induce maturation.
Brachet,
A cytochemical and ultrastructural analysis of in vitro maturation in amphibian oocytes.
1970, Pubmed
Brachet,
A cytochemical and ultrastructural analysis of in vitro maturation in amphibian oocytes.
1970,
Pubmed Brachet,
Biochemical changes during progesterone-induced maturation in Xenopus laevis oocytes.
1974,
Pubmed
,
Xenbase Hanocq,
Cytochemical and biochemical studies on progesterone-induced maturation in amphibian oocytes. 2. DNA synthesis.
1974,
Pubmed
,
Xenbase Hellman,
The pancreatic -cell recognition of insulin secretagogues. VII. Binding and permeation of chloromercuribenzene-p-sulphonic acid in the plasma membrane of pancreatic -cells.
1973,
Pubmed Jacobelli,
Hormone-induced maturation of Xenopus laevis oocytes: effects of different steroids and study of the properties of a progesterone receptor.
1974,
Pubmed
,
Xenbase Kishimoto,
Induction of starfish oocyte maturation by disulfide-reducing agents.
1973,
Pubmed Masui,
Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes.
1971,
Pubmed Merriam,
Progesterone-induced maturational events in oocytes of Xenopus laevis. I. Continuous necessity for diffusible calcium and magnesium.
1971,
Pubmed
,
Xenbase Ozon,
Progesterone receptor associated with the "melanosome" fraction of Pleurodeles waltlii oocytes (Urodela amphibian).
1973,
Pubmed Reynhout,
Studies on the appearance and nature of a maturation-inducing factor in the cytoplasm of amphibian oocytes exposed to progesterone.
1974,
Pubmed
,
Xenbase Schorderet-Slatkine,
Action of progesterone and related steroids on oocyte maturation in Xenopus laevis. An in vitro study.
1972,
Pubmed
,
Xenbase Schorderet-Slatkine,
Progesterone induced maturation in oocytes of Xenopus laevis. Appearance of a 'maturation promoting factor' in enucleated oocytes.
1973,
Pubmed
,
Xenbase Schuetz,
Role of hormones in oocyte maturation.
1974,
Pubmed Smith,
The interaction of steroids with Rana pipiens Oocytes in the induction of maturation.
1971,
Pubmed Smith,
Regulatory processes in the maturation and early cleavage of amphibian eggs.
1970,
Pubmed Steinert,
Ultrastructure of Xenopus laevis oocytes after injection of an extract from progesterone-treated oocytes.
1974,
Pubmed
,
Xenbase Steinhardt,
Is calcium ionophore a universal activator for unfertilised eggs?
1974,
Pubmed
,
Xenbase Wallace,
Protein incorporation by isolated amphibian oocytes. 3. Optimum incubation conditions.
1973,
Pubmed
,
Xenbase
