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Analysis of the C-value paradox by molecular hybridization.
Rosbash M, Ford PJ, Bishop JO.
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Poly(A)-containing RNA was isolated from ovaries of Xenopus laevis laevis and Triturus cristatus carnifex and used as a template for the synthesis of radioactive complementary DNA with RNA-dependent DNA polymerase. When annealed with an excess of homologous DNA, the complementary DNA is rendered double-stranded with kinetics that suggest that the coding sequences are single-copy in both these organisms. In Triturus, these sequences are distinct from the majority of the genome, which consists of repeated sequences, and distinct from the ribosomal cistrons, which are present in proportion to the increase in C-value relative to the Xenopus genome. Moreover, the number of different poly(A)-containing molecules in the ovary (sequence complexity) is the same in Xenopus and in Triturus.
Adesnik,
Evidence that all messenger RNA molecules (except histone messenger RNA) contain Poly (A) sequences and that the Poly(A) has a nuclear function.
1972, Pubmed
Adesnik,
Evidence that all messenger RNA molecules (except histone messenger RNA) contain Poly (A) sequences and that the Poly(A) has a nuclear function.
1972,
Pubmed Aviv,
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.
1972,
Pubmed Bishop,
Molecular hybridization of ribonucleic acid with a large excess of deoxyribonucleic acid.
1972,
Pubmed Bishop,
Reiteration frequency of haemoglobin genes in the duck.
1972,
Pubmed Bishop,
Reiteration frequency of duck haemoglobin genes.
1973,
Pubmed Bonner,
Reduction in the rate of DNA reassociation by sequence divergence.
1973,
Pubmed Brawerman,
Eukaryotic messenger RNA.
1974,
Pubmed Buongiorno-Nardelli,
Amplification as a rectification mechanism for the redundant rRNA genes.
1972,
Pubmed
,
Xenbase Callan,
The organization of genetic units in chromosomes.
1967,
Pubmed Davidson,
General interspersion of repetitive with non-repetitive sequence elements in the DNA of Xenopus.
1973,
Pubmed
,
Xenbase Davidson,
Genetic information in oocyte RNA.
1971,
Pubmed Davidson,
Organization, transcription, and regulation in the animal genome.
1973,
Pubmed
,
Xenbase Davidson,
High sequence diversity in the RNA synthesized at the lampbrush stage of oögenesis.
1969,
Pubmed
,
Xenbase Dawid,
Deoxyribonucleic acid in amphibian eggs.
1965,
Pubmed Gelderman,
Transcription of nonrepeated DNA in neonatal and fetal mice.
1971,
Pubmed Goldberg,
Nonrepetitive DNA sequence representation in sea urchin embryo messenger RNA.
1973,
Pubmed Greenberg,
Relative occurrence of polyadenylic acid sequences in messenger and heterogeneous nuclear RNA of L cells as determined by poly (U)-hydroxylapatite chromatography.
1972,
Pubmed Greenberg,
Hybridization properties of DNA sequences directing the synthesis of messenger RNA and heterogeneous nuclear RNA.
1971,
Pubmed Kacian,
Purification of the DNA polymerase of avian myeloblastosis virus.
1971,
Pubmed KIRBY,
ISOLATION AND CHARACTERIZATION OF RIBOSOMAL RIBONUCLEIC ACID.
1965,
Pubmed Melli,
DNA-RNA hybridization in vast DNA excess.
1971,
Pubmed MIRSKY,
The desoxyribonucleic acid content of animal cells and its evolutionary significance.
1951,
Pubmed Perry,
Synthesis and turnover of nuclear and cytoplasmic polyadenylic acid in mouse L cells.
1974,
Pubmed Rosbash,
Polyadenylic acid-containing RNA in Xenopus laevis oocytes.
1974,
Pubmed
,
Xenbase Ruprecht,
Conditions for the selective synthesis of DNA complementary to template RNA.
1973,
Pubmed Schildkraut,
Dependence of the melting temperature of DNA on salt concentration.
1965,
Pubmed Straus,
Comparative DNA renaturation kinetics in amphibians.
1971,
Pubmed STUDIER,
SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA.
1965,
Pubmed Sutton,
A crude nuclease preparation suitable for use in DNA reassociation experiments.
1971,
Pubmed
