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XB-ART-3851
Pigment Cell Res 2004 Apr 01;172:119-27. doi: 10.1046/j.1600-0749.2003.00115.x.
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The spleen pigment cells in some amphibia.

Scalia M, Di Pietro C, Poma M, Ragusa M, Sichel G, Corsaro C.


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It was demonstrated that the spleen pigment cells of Amphibia are macrophages: they show an ultrastructurally distinctive morphology, are able to phagocytose and react positively for non-specific esterases. These pigmented macrophages express mRNA for tyrosinase and also they show dopa oxidase activity; therefore they are able to synthesize melanins, as Kupffer cells do.

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