Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
In this issue of Molecular Cell, Kimata et al. (2008) show that Cdc20 functions not only in the recruitment of substrates to the anaphase-promoting complex but also in its activation.
Au,
Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit.
2002, Pubmed
Au,
Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit.
2002,
Pubmed Carroll,
The APC subunit Doc1 promotes recognition of the substrate destruction box.
2005,
Pubmed Carroll,
The Doc1 subunit is a processivity factor for the anaphase-promoting complex.
2002,
Pubmed Dube,
Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.
2005,
Pubmed
,
Xenbase Hayes,
Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C.
2006,
Pubmed
,
Xenbase Kimata,
A role for the Fizzy/Cdc20 family of proteins in activation of the APC/C distinct from substrate recruitment.
2008,
Pubmed
,
Xenbase Passmore,
Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.
2003,
Pubmed Thornton,
An architectural map of the anaphase-promoting complex.
2006,
Pubmed Thornton,
Precise destruction: an emerging picture of the APC.
2006,
Pubmed Wendt,
Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex.
2001,
Pubmed Yamano,
Cell cycle-regulated recognition of the destruction box of cyclin B by the APC/C in Xenopus egg extracts.
2004,
Pubmed
,
Xenbase
