Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
Some epithelia contain cells with multiple motile cilia that beat in a concerted manner. New tools and experimental systems have facilitated molecular studies of cilium biogenesis and the coordinated planar polarization of cilia that leads to their concerted motility. A recent elegant study using embryonic frog epidermis demonstrates that Dishevelled, a key regulator of both the Wnt-beta-catenin and planar cell polarity pathways, controls both the docking and planar polarization of ciliary basal bodies.
Boisvieux-Ulrich,
Determination of ciliary polarity precedes differentiation in the epithelial cells of quail oviduct.
1991, Pubmed
Boisvieux-Ulrich,
Determination of ciliary polarity precedes differentiation in the epithelial cells of quail oviduct.
1991,
Pubmed Boisvieux-Ulrich,
The orientation of ciliary basal bodies in quail oviduct is related to the ciliary beating cycle commencement.
1985,
Pubmed Boisvieux-Ulrich,
Cytochalasin D inhibits basal body migration and ciliary elongation in quail oviduct epithelium.
1990,
Pubmed Classen,
Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway.
2005,
Pubmed Gomperts,
Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells.
2004,
Pubmed Gromley,
Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission.
2005,
Pubmed Habas,
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1.
2001,
Pubmed
,
Xenbase Hagiwara,
Cell biology of normal and abnormal ciliogenesis in the ciliated epithelium.
2004,
Pubmed Marshall,
The cell biological basis of ciliary disease.
2008,
Pubmed Mitchell,
A positive feedback mechanism governs the polarity and motion of motile cilia.
2007,
Pubmed
,
Xenbase Pan,
RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1.
2007,
Pubmed Park,
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells.
2008,
Pubmed
,
Xenbase Park,
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling.
2006,
Pubmed
,
Xenbase Qian,
Wnt5a functions in planar cell polarity regulation in mice.
2007,
Pubmed
,
Xenbase Ross,
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates.
2005,
Pubmed Saburi,
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.
2008,
Pubmed Seifert,
Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility.
2007,
Pubmed Shimada,
Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium.
2006,
Pubmed Sorokin,
Centriole formation and ciliogenesis.
1968,
Pubmed Vladar,
Molecular characterization of centriole assembly in ciliated epithelial cells.
2007,
Pubmed Wu,
The ghost in the machine: small GTPases as spatial regulators of exocytosis.
2008,
Pubmed Zallen,
Planar polarity and tissue morphogenesis.
2007,
Pubmed