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XB-ART-40688
Opt Lett 1996 Sep 01;2117:1408-10. doi: 10.1364/ol.21.001408.
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Rapid acquisition of in vivo biological images by use of optical coherence tomography.

Tearney GJ, Bouma BE, Boppart SA, Golubovic B, Swanson EA, Fujimoto JG.


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The development of techniques for high-speed image acquisition in optical coherence tomography (OCT) systems is essential for suppressing motion artifacts when one is imaging living systems. We describe a new OCT system for performing micrometer-scale, cross-sectional optical imaging at four images/s. To achieve OCT image-acquisition times of less than 1 s, we use a piezoelectric fiber stretcher to vary the reference arm delay. A Kerr-lens mode-locked chromium-doped forsterite laser is employed as the low-coherence source for the highspeed OCT system. Dynamic, motion-artifact-free in vivo imaging of a beating Xenopus laevis (African frog) heart is demonstrated.

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