Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
Immunoreactive platelet-derived growth factor-AB and transforming growth factor-beta 1 were demonstrated in invertebrate and vertebrate immunocytes by an immunocytochemical procedure. These factors are only present in phagocytic cells among invertebrate immunocytes, whereas in vertebrate immunocytes they are found in monocytes, granulocytes, lymphocytes, thrombocytes and platelets. These results, in agreement with previous reports, represent further evidence in favour of the hypothesis that Nature has followed a conservative strategy in using a common pool of signal molecules that have been highly conserved throughout evolution.
Assoian,
Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.
1986, Pubmed
Assoian,
Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.
1986,
Pubmed Beck,
Characterization of interleukin-1 activity in tunicates.
1989,
Pubmed Beck,
Isolation and characterization of a primitive interleukin-1-like protein from an invertebrate, Asterias forbesi.
1986,
Pubmed Betsholtz,
cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines.
,
Pubmed Bressler,
Chemotaxis of rat brain astrocytes to platelet derived growth factor.
1985,
Pubmed Deuel,
Chemotaxis of monocytes and neutrophils to platelet-derived growth factor.
1982,
Pubmed Franchini,
Induction of ACTH- and TNF-alpha-like molecules in the hemocytes of Calliphora vomitoria (Insecta, Diptera).
1996,
Pubmed Granath,
Interleukin 1 activity in haemolymph from strains of the snail Biomphalaria glabrata varying in susceptibility to the human blood fluke, Schistosoma mansoni: presence, differential expression, and biological function.
1994,
Pubmed Grotendorst,
Platelet-derived growth factor is a chemoattractant for vascular smooth muscle cells.
1982,
Pubmed Hart,
Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets.
1990,
Pubmed Hughes,
Immunoreactive cytokines in Mytilus edulis nervous and immune interactions.
1992,
Pubmed Hughes,
Interaction of immunoactive monokines (interleukin 1 and tumor necrosis factor) in the bivalve mollusc Mytilus edulis.
1990,
Pubmed Kletsas,
The growth-inhibitory block of TGF-beta is located close to the G1/S border in the cell cycle.
1995,
Pubmed Massagué,
Transforming growth factor-beta.
1992,
Pubmed Mellstroöm,
The effect of platelet-derived growth factor on morphology and motility of human glial cells.
1983,
Pubmed Morgese,
Microglial movement to sites of nerve lesion in the leech CNS.
1983,
Pubmed Ottaviani,
ACTH-like molecules in lymphocytes. A study in different vertebrate classes.
1992,
Pubmed Ottaviani,
CRF provokes the release of norepinephrine by hemocytes of Viviparus ater (Gastropoda, Prosobranchia): further evidence in favour of the evolutionary hypothesis of the mobile immune-brain.
1993,
Pubmed Ottaviani,
Relationship between corticotropin-releasing factor and interleukin-2: evolutionary evidence.
1994,
Pubmed Ottaviani,
Stress response in the freshwater snail Planorbarius corneus (L.) (Gastropoda, Pulmonata): interaction between CRF, ACTH, and biogenic amines.
1992,
Pubmed Ottaviani,
The blood cells of the freshwater snail Planorbis corneus (Gastropoda, Pulmonata).
1983,
Pubmed Ottaviani,
The neuroimmunology of stress from invertebrates to man.
1996,
Pubmed Ottaviani,
Cytokines and evolution: in vitro effects of IL-1 alpha, IL-1 beta, TNF-alpha and TNF-beta on an ancestral type of stress response.
1995,
Pubmed Ottaviani,
Cytokines and invertebrate immune responses.
1995,
Pubmed Ottaviani,
Presence of several cytokine-like molecules in molluscan hemocytes.
1993,
Pubmed Ouwe-Missi-Oukem-Boyer,
Characterization of immunoreactive TNF alpha molecules in the gastropod Biomphalaria glabrata.
1994,
Pubmed Paemen,
Glial localization of interleukin-1 alpha in invertebrate ganglia.
1992,
Pubmed Raftos,
Invertebrate cytokines: tunicate cell proliferation stimulated by an interleukin 1-like molecule.
1991,
Pubmed Richardson,
A role for platelet-derived growth factor in normal gliogenesis in the central nervous system.
1988,
Pubmed Roberts,
Transforming growth factor beta.
1988,
Pubmed Ross,
The biology of platelet-derived growth factor.
1986,
Pubmed Singh,
Phylogenetic analysis of platelet-derived growth factor by radio-receptor assay.
1982,
Pubmed Sonetti,
Microglia in invertebrate ganglia.
1994,
Pubmed Stathakos,
Stimulation of human embryonic lung fibroblasts by TGF-beta and PDGF acting in synergism. The role of cell density.
1993,
Pubmed Stefano,
Opioid induction of immunoreactive interleukin-1 in Mytilus edulis and human immunocytes: an interleukin-1-like substance in invertebrate neural tissue.
1991,
Pubmed Wahl,
Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.
1987,
Pubmed
