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Lab Chip
2013 Nov 07;1321:4160-3. doi: 10.1039/c3lc50571e.
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A novel approach to quantifying ciliary physiology: microfluidic mixing driven by a ciliated biological surface.
Jonas S, Zhou E, Deniz E, Huang B, Chandrasekera K, Bhattacharya D, Wu Y, Fan R, Deserno TM, Khokha MK, Choma MA.
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From the lungs to the central nervous system, cilia-driven fluid flow plays a fundamental role in many facets of life. Yet, there are few quantitative methods for analysing the function of ciliated surfaces. Here, we report a novel microfluidic approach for quantifying the performance of a ciliated surface using mixing performance as an integrated readout.
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