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Endoplasmic reticulum (ER) sheet membranes are covered with ribosomes and RNAs that are involved in protein synthesis. A new study reveals that a calcium-activated endoribonuclease of the EndoU protein family promotes the formation of tubular ER networks, contributing to dynamic shaping of the ER in cells.
Blackstone,
Cellular pathways of hereditary spastic paraplegia.
2012, Pubmed
Blackstone,
Cellular pathways of hereditary spastic paraplegia.
2012,
Pubmed English,
Endoplasmic reticulum structure and interconnections with other organelles.
2013,
Pubmed Falabella,
Functional amyloids in insect immune response.
2012,
Pubmed Gioia,
Functional characterization of XendoU, the endoribonuclease involved in small nucleolar RNA biosynthesis.
2005,
Pubmed
,
Xenbase Goyal,
Untangling the web: mechanisms underlying ER network formation.
2013,
Pubmed Hu,
A class of dynamin-like GTPases involved in the generation of the tubular ER network.
2009,
Pubmed Hübner,
Membrane-shaping disorders: a common pathway in axon degeneration.
2014,
Pubmed Kucharz,
NMDA receptor stimulation induces reversible fission of the neuronal endoplasmic reticulum.
2009,
Pubmed Orso,
Homotypic fusion of ER membranes requires the dynamin-like GTPase atlastin.
2009,
Pubmed Park,
Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER network.
2010,
Pubmed Poe,
EndoU is a novel regulator of AICD during peripheral B cell selection.
2014,
Pubmed Ragno,
Identification of small-molecule inhibitors of the XendoU endoribonucleases family.
2011,
Pubmed
,
Xenbase Ricagno,
Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family.
2006,
Pubmed Schlaitz,
REEP3/4 ensure endoplasmic reticulum clearance from metaphase chromatin and proper nuclear envelope architecture.
2013,
Pubmed Schwarz,
The calcium-dependent ribonuclease XendoU promotes ER network formation through local RNA degradation.
2014,
Pubmed
,
Xenbase Shibata,
Mechanisms determining the morphology of the peripheral ER.
2010,
Pubmed Subramanian,
Calcium-induced restructuring of nuclear envelope and endoplasmic reticulum calcium stores.
1997,
Pubmed Terasaki,
Structural change of the endoplasmic reticulum during fertilization: evidence for loss of membrane continuity using the green fluorescent protein.
1996,
Pubmed Voeltz,
A class of membrane proteins shaping the tubular endoplasmic reticulum.
2006,
Pubmed Wang,
Local zones of endoplasmic reticulum complexity confine cargo in neuronal dendrites.
2012,
Pubmed
