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Nat Cell Biol
2016 May 27;186:593-4. doi: 10.1038/ncb3367.
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Replicating repetitive DNA.
Tognetti S, Speck C.
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The function and regulation of repetitive DNA, the 'dark matter' of the genome, is still only rudimentarily understood. Now a study investigating DNA replication of repetitive centromeric chromosome segments has started to expose a fascinating replication program that involves suppression of ATR signalling, in particular during replication stress.
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