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XB-ANTIBODY-17311775
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Antibody Name:
Aurka Ab5
Common Name: Aurora A RRID: Synonyms: Eg2, sc-27884
Source: |
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| Antibody | |
| Clone Number | xG-14 |
| Purification | |
| Isotype | IgG |
| Host Organism | goat |
| Xenopus Reactivity | X. tropicalis, X. laevis |
| Non-Xenopus Reactivity | |
| Description: | Santa Cruz Biotechnology |
| Immunogen | |
| Name | aurka |
| Type | polypeptide |
| Post Translational Modifications | None |
| Source Organism | frog |
| Description | Activation of the oncogenic protein kinase Aurora A regulates meiotic and mitotic cell cycles in eukaryotic cells. Specifically, Aurora A plays a key role in G2/M progression. Activation occurs via autophosphorylation, and while 14 sites are subject to this, only the threonine residue at position 295 is required for activity. Though autophosphorylation mediates activation, a number of other proteins influence activation, including the spindle assembly factor TPX2 and p53. |
| Sequence | |
| Reported Usage | |
| Publications | |
| ???displayAntibody.papersFirst??? |
Xenopus laevis as a Model to Identify Translation Impairment., J Vis Exp 2015 |
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