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Summary Expression Phenotypes Gene Literature (6) GO Terms (21) Nucleotides (42) Proteins (28) Interactants (103) Wiki
XB-GENEPAGE-958328
???displayGene.symbol???:
 tph2

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tryptophan hydroxylase 2

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LOC108710258 ( Nomenclature history )

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Aromatic amino acid hydroxylase

AI Protein Function :
The tph2 gene encodes tryptophan hydroxylase 2, which catalyzes the rate-limiting step in serotonin synthesis. In Xenopus laevis and tropicalis, it is expressed in the brain, particularly in the raphe ...[+]


InterPro :
TrpOH cat, Trp 5 mOase, Tyrosine 3-monooxygenase-like, ArAA hydroxylase, [+]

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Diseases: 


Disease Ontology:
melancholic depression

MIM:
MAJOR DEPRESSIVE DISORDER; MDD [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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