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Summary Expression Phenotypes Gene Literature (8) GO Terms (94) Nucleotides (104) Proteins (52) Interactants (406) Wiki
XB-GENEPAGE-492533
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 adam17

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ADAM metallopeptidase domain 17

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adam18 , cd156b , csvp , tace ( Nomenclature history )

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disintegrin metalloprotease

AI Protein Function :
The adam17 protein is a transmembrane metalloprotease localized to the plasma membrane. It functions in ectodomain shedding of epidermal growth factor receptor ligands and regulates cell signaling duri...[+]


InterPro :
MetalloPept cat dom sf, ADAM17 MPD, Disintegrin dom sf, ADAM10 ADAM17, [+]

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Diseases: 


MIM:
INFLAMMATORY SKIN AND BOWEL DISEASE, NEONATAL, 1; NISBD1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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