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Summary Expression Phenotypes Gene Literature (6) GO Terms (44) Nucleotides (163) Proteins (55) Interactants (327) Wiki
XB-GENEPAGE-479288
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 sufu

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SUFU negative regulator of hedgehog signaling

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sufuh , sufuxl , Xsufu ( Nomenclature history )

AI Protein Function :
The sufu protein functions as a suppressor of hedgehog signaling by binding to gli transcription factors in the cytoplasm, preventing their nuclear translocation and activation of target genes. It loca...[+]


InterPro :
Suppressor of fused euk, SUFU-like domain, SUFU C, SUFU C sf, [+]

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Diseases: 


Disease Ontology:
medulloblastoma [+]

MIM:
MEDULLOBLASTOMA; MDB [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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