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Summary Expression Phenotypes Gene Literature (62) GO Terms (9) Nucleotides (33) Proteins (17) Interactants (662) Wiki
XB-GENEPAGE-6054494
???displayGene.symbol???:
 ptpn11

???displayGene.name???: 
protein tyrosine phosphatase, non-receptor type 11

???displayGene.synonyms???
bptp3 , cfc , corkscrew , csw , LOC108716965 , ns1 [+] ( Nomenclature history )

???displayGene.geneFunction???
codes for a signaling molecule that is predicted to regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation

AI Protein Function :
The ptpn11 gene encodes a non-membrane spanning protein tyrosine phosphatase which contains two SH2 domains and is involved in ras/MAPK signaling downstream of receptor tyrosine kinases. It is expresse...[+]


InterPro :
Prot-tyrosine phosphatase-like, PTP cat, SH2, SH2 dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
juvenile myelomonocytic leukemia [+]

MIM:
JUVENILE MYELOMONOCYTIC LEUKEMIA; JMML [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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