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Summary Expression Phenotypes Gene Literature (7) GO Terms (22) Nucleotides (95) Proteins (61) Interactants (219) Wiki
XB-GENEPAGE-6039486
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 plekhg5

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pleckstrin homology and RhoGEF domain containing G5

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( Nomenclature history )

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Predicted guanine nucleotide exchange factor

AI Protein Function :
The plekhg5 protein is a rho guanine nucleotide exchange factor (rhoGEF) that exhibits GEF activity towards RhoA and Cdc42. It localizes to the plasma membrane through its PH domain. Expression is dete...[+]


InterPro :
DH-domain, PH domain, DBL dom sf, Ubiquitin-like domsf, [+]

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Diseases: 


Disease Ontology:
Charcot-Marie-Tooth disease recessive intermediate C [+]

MIM:
NEURONOPATHY, DISTAL HEREDITARY MOTOR, AUTOSOMAL RECESSIVE 4; HMNR4 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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