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Summary Expression Phenotypes Gene Literature (24) GO Terms (78) Nucleotides (305) Proteins (57) Interactants (549) Wiki
XB-GENEPAGE-6258451
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 cbl

???displayGene.name???: 
Cbl proto-oncogene, E3 ubiquitin protein ligase

???displayGene.synonyms???
c-cbl , rnf55 ( Nomenclature history )

AI Protein Function :
The cbl protein acts as an e3 ubiquitin ligase, targeting receptor tyrosine kinases for degradation and negatively regulating rtk signaling pathways. It is expressed in the neural crest cells, pronephr...[+]


InterPro :
Znf RING, Adaptor Cbl SH2-like, SH2 dom sf, Znf RING CS, [+]

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Diseases: 


Disease Ontology:
juvenile myelomonocytic leukemia

MIM:
JUVENILE MYELOMONOCYTIC LEUKEMIA; JMML [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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