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Summary Expression Phenotypes Gene Literature (14) GO Terms (70) Nucleotides (366) Proteins (50) Interactants (150) Wiki
XB-GENEPAGE-945387
???displayGene.symbol???:
 adam10

???displayGene.name???: 
ADAM metallopeptidase domain 10

???displayGene.synonyms???
ad10 , cd156c , kuz , kuzbanian , LOC108711361 , madm [+] ( Nomenclature history )

???displayGene.geneFunction???
Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases

AI Protein Function :
The adam10 gene encodes a membrane-anchored metalloprotease involved in the proteolytic processing of various substrates, a process known as ectodomain shedding. Its functions include promoting neuroge...[+]


InterPro :
MetalloPept cat dom sf, Peptidase M12B N, Peptidase M12B, Disintegrin dom sf, [+]

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Diseases: 


Disease Ontology:
reticulate acropigmentation of Kitamura [+]

MIM:
ALZHEIMER DISEASE 18; AD18 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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